113 Effects of Maternal Parity and Prebiotics on the Microbiome of Nursery Pigs

Abstract The objective of this study was to investigate the effect maternal parity on sow and offspring microbiomes, influence pig fecal microbiome performance in response a prebiotic post-weaning. Fecal vaginal swabs were collected from 22 primiparous 74 multiparous sows commercial farm at weaning. also 48 randomly selected piglets (n = 24, respectively) d 0, 21, 42 At weaning, allotted into 3 dietary treatment groups: standard nursery diet including pharmacological doses Zn Cu (CTRL), group fed only (PRE), plus (PRE+ZnCu). Extracted DNA sequenced MiSeq platform targeting V4 variable region 16S rRNA bacterial gene, sequence data analyzed using DADA2 various packages within R statistical software. Although there no differences composition between sows, different (PERMANOVA, R2 0.02, P 0.03). microbiomes displayed significantly higher diversity compared with d0 d21 (Shannon’s H, < 0.01), community observed 0.03, 0.04). When analyzing effects each treatment, PRE showed significant compositional distinctions (d21: PERMANOVA, 0.13, 0.01; d42: 0.19, 0.001). Compositional treatments, regardless parity, 0.12, No growth groups observed. These results indicate that influences gut post-weaning, may prebiotics microbiomes.